A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine.

نویسندگان

  • Jingyan Ge
  • Lin Li
  • Shao Q Yao
چکیده

Synthesis of the first self-immobilizing, fluorogenic unnatural amino acid that mimics phosphotyrosine (pTyr) is reported. By using solid-phase peptide synthesis, it was subsequently incorporated into peptide-based probes which found applications in bioimaging and fluorescence-activated cell sorting (FACS).

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عنوان ژورنال:
  • Chemical communications

دوره 47 39  شماره 

صفحات  -

تاریخ انتشار 2011